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EASO recommends semaglutide and tirzepatide as first-line treatment for obesity owenhaskins Oct 1, 2025 5 min read Semaglutide or tirzepatide should be the first line treatment for people living with obesity and most of its complications, according to a framework for the pharmacological treatment of obesity and its complications from the European Association for the Study of Obesity (EASO), published in the journal Nature
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